Lay media work with stem cell (SC) therapy has generally devoted to two areas:
1. The promise of embryonic SC
2. The proliferation of charlatans preying afterward you dreams and fears of helpless patients.
While embryonic SOUTH CAROLINA, in theory, appear to potentially be the ideal option for tissue regrowth, the hype has exceeded anticipation. Because of political don't forget that ethical concerns, research efforts with your cells has been frustrating.
At the same years, news articles and television commentaries have also dealt with controversial instances SC therapy. An inordinate stretch of time has been devoted to qualify for the exposing the seamy part... individuals involved in wise hucksterism, the possible maltreatment of SC therapy via practitioners, as well among the implication that all SOUTH CAROLINA research conducted outside academics centers is suspect.
As an effect, there has been neglect regarding of a few fascinating and promising transact, particularly in arthritis treatment.
One of the that much more intriguing studies was recently written by Korean investigators (Pak T. Regeneration of human bone tissues in hip osteonecrosis maybe human cartilage in leg osteoarthritis with autologous adipose-derived peel cells: a case rounds. J Med Case Disclosures. 2011; 7: 296)
The Mandarin chinese physicians treated four members. Two (a 29 years old woman and a 47 year old man) had osteonecrosis throughout the hip. Two other patients (a 70 years old woman and a 79 year old man) had osteoarthritis throughout the knee. They were all given distinctive autologous stem cells (the patient's own stem cells) contingent on fat along with platelet that are rich plasma, hyaluronic acid, nanogram amounts of dexamethasone, and calcium chloride.
Pre and post approach MRI scans were specific to all subjects. In simply of patients with osteonecrosis, teen bone formation was noted earlier. In the patients with osteoarthritis, new cartilage manufacturing was seen.
Along for your MRI findings, both subjective pain measures and makeup outcomes improved.
I found these findings to get it extremely interesting for assorted reasons.
First, the mixture used in the Korean report is similar to the one that i'll use at our lifeblood, with one exception. The exception this particular: In addition to everything SC, we also press bone marrow derived root cells.
And, while our center has had excellent results with nck osteoarthritis (more than 90 per cent success), our experience with both hip osteoarthritis probable disappointment hip osteonecrosis has spoke disappointing.
Why the difference between hip and knee? I suspect the reason is , the mechanical forces will vary. The anatomy of newborn hip joint allows extreme rotation in comparison to the knee joint which is especially a hinge joint if you do rotation and some sliding. Activity level and body weight may also be contributing factors.
Nonetheless, this report from Korea underscores what we believe really was... the use of autologous root cells, also known that being said repair stem cells, will turned out to be a fruitful area which experts state progress in osteoarthritis research for years to come.
.
No comments:
Post a Comment